论文部分内容阅读
维甲酸（ＨＲＡ）是维生素Ａ的不饱和一元酸．它不仅对急性早幼粒白血病（ＡＰＬ）有特异性的治疗作用，完全缓解率高达８５％以上［１］，对其它肿瘤也有一定的抑制作用［２，３］，被誉为最有希望的一类抗肿瘤新药．但毒副作用较大，因而不能大剂量、广泛地应用于临床．维甲
Retinoic acid (HRA) is an unsaturated monobasic acid of vitamin A. It not only has a specific therapeutic effect on acute promyelocytic leukemia (APL), with a complete remission rate of more than 85% [1], but also has certain inhibitory effects on other tumors [2,3], which has been hailed as the most promising A class of anti-tumor drugs. However, toxic side effects, which can not be large doses, widely used in clinical. Weijia