肝脏是人体内最重要的代谢器官,几乎参于体内的一切代谢过程,故有“物质代谢中枢”之称。绝大部分药物的代谢与消除和肝脏有关。药物作用的强弱,维持时间的长短,毒性大小等在相当程度上取决于肝脏的功能状态。因此,肝脏和临床用药的关系甚为密切。另外,不少药物对肝脏有毒性,会不同程度地损害肝脏功能。 The liver is the body’s most important metabolic organs, almost all involved in the body’s metabolic processes, it is “material metabolism center,” said. The vast majority of drug metabolism and elimination and the liver. The strength of the drug, the duration of the maintenance, the size of the toxicity and so on, to a large extent depend on the functional status of the liver. Therefore, the relationship between liver and clinical medication is very close. In addition, many drugs are toxic to the liver, will damage the liver function to varying degrees.