论文部分内容阅读
目的研究急性颅脑创伤病人垂体前叶黄体生成素(luteinizing hormone,LH)的动态变化及其对病情及预后的评估。方法随机选取1999年12月至2001年6月间急性颅脑创伤住院病人50例,按照GCS分数、GOS不同的预后、不同的创伤类型、CT中线移位程度等因素分别进行了分析研究。同时设立对照组12例。结果颅脑创伤组LH值明显高于正常对照组。颅脑创伤的程度越重,伤后即刻的LH值越高,而动态观察则快速下降,波动幅度大,其伤后入院即刻检测值与入院第 3天的检测值之比值也就越大。如GCS 3～5分组,死亡组,重度中线移位组,脑挫伤组的情况都是如此。伤情较轻者,黄体生成素升高的程度较小,且伤后48 h逐渐恢复正常,波动幅度小,其伤后入院即刻检测值与伤后入院第3天的检测值之比值也就越小。结论颅脑创伤病人伤后LH的动态变化可以作为伤情判断和判断预后的重要指标之一。凡伤后LH明显升高而48 h后明显降低者,入院检测的LH值与入院后72 h所检测的LH比值大于3者,预示伤情严重且预后不良。
Objective To study the dynamic changes of luteinizing hormone (LH) in the anterior pituitary of acute craniocerebral trauma patients and its assessment on the condition and prognosis. Methods Fifty patients with acute traumatic brain injury in our hospital from December 1999 to June 2001 were randomly selected and analyzed according to factors such as GCS score, different prognosis of GOS, different types of trauma and CT midline displacement. At the same time set up a control group of 12 cases. Results The LH value in traumatic brain injury group was significantly higher than that in normal control group. The greater the degree of traumatic brain injury, the higher the value of LH immediately after injury, while the dynamic observation decreased rapidly with a large fluctuation range. The ratio of the immediately detected value after injury and the detected value on the 3rd day after admission was greater. Such as GCS 3 to 5 groups, death group, severe midline shift group, brain contusion group are the case. Lesser injury, lutealizing hormone increased to a lesser extent, and 48 h after injury gradually returned to normal, the fluctuation range is small, the injury immediately after admission to the hospital the detection value and admission injury on the 3rd day of the test value ratio The smaller. Conclusion The dynamic changes of LH after craniocerebral trauma patients may be used as one of the important indicators to judge the injury and prognosis. Where post-injury LH increased significantly after 48 h and decreased significantly, admission LH values ?? measured and 72 h after admission LH ratio of more than 3 tests, indicating a serious injury and poor prognosis.