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利用计算机同源模建预测人微小纤溶酶原的三维结构,与葡激酶X射线晶体结构进行了分子对接,研究了葡激酶与微小溶酶原的结合区,并设计了分子量小、低抗原性的新型葡激酶分子,为开发口服溶栓药物奠定了基础
Using computer homology modeling to predict the three-dimensional structure of human miniplasinogen and molecular docking with staphylokinase X-ray crystal structure, the binding region of staphylokinase with mino prime was studied, and the molecular weight of small, low antigen The new type of staphylokinase molecules laid the foundation for the development of oral thrombolytic drugs