本文报告了57例神经纤维瘤病,男26例,女31例,年龄1～76岁(平均27.3岁)。作者指出,本病主要以皮肤色素沉着、多发性软性皮肤肿瘤、末梢神经纤维瘤为主要临床征象。现在,一般认为本病系外胚叶、中胚叶、及内胚叶组织的异常形成为基础的遗传性、家族性的全身系统疾病,病因为常 This article reports 57 cases of neurofibromatosis, 26 males and 31 females, aged 1 to 76 years (mean 27.3 years). The authors pointed out that the main clinical manifestations of this disease are skin pigmentation, multiple soft skin tumors and peripheral nerve fibers. At present, it is generally considered that this disease is a hereditary and familial systemic disease based on abnormal formation of epiblast, mesodermal, and endoderm tissues.