大量骨质溶解症(亦称急性自发性骨吸收、骨消失症或幻影骨)是一种罕见病。多见于上下肢带的骨骼,累及胸、肋、胸椎者极少,偶见侵犯上下颌骨及硬腭、蝶骨。国内曾有1例侵及颌骨的报道。本病病因尚不明确,可能与①感染,如类风湿性关节炎;②中枢神经系统疾病;③无菌性坏死;④牛皮癣性关节病;⑤血管瘤病(可并发淋巴管病)等有关。溶骨症多发生于青少年及儿童,进展缓慢,可有数年或数十年病程;亦有可能自行停止发展。患部无力、疼 A large number of osteolytic (also known as acute spontaneous bone resorption, bone loss or phantom bones) is a rare disease. More common in the upper and lower extremity with the skeleton, involving the chest, ribs, thoracic rarely, sometimes violated the mandible and palate, sphenoid. There was a case of domestic invasion of the jaw bone. The etiology of this disease is not yet clear, may be related to ① infection, such as rheumatoid arthritis; ② central nervous system diseases; ③ aseptic necrosis; ④ psoriatic arthropathy; ⑤ hemangiomatosis (which can be complicated by lymphangitic disease) and other related . Osteolytic disease occurs in adolescents and children, progress is slow, may have a few years or decades of disease; may also stop development on their own. Affected patients weakness, pain