带状疱疹是由水痘-带状疱疹病毒引起的皮肤科常见病,阿昔洛韦是最常用的抗病毒药物,有较好的临床疗效。但其主要是经肾小球过滤和肾小管分泌后从尿中排出,到达肾小管腔的浓度较高,60%～90%以原形从肾脏排泄。本品在尿中相对不溶,特别是在尿流下降的远曲小管腔,可致肾 Shingles is a common dermatitis caused by varicella-zoster virus. Acyclovir is the most commonly used antiviral drug and has good clinical efficacy. However, it is mainly excreted through the glomerular filtration and tubular secretion from the urine to reach the high concentration of the renal tubules, 60% to 90% of the prototype from the kidneys excretion. This product is relatively insoluble in urine, especially in the far stream of urine decline in small lumen, can cause kidney