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目的观察311例泌尿生殖道支原体、衣原体感染情况,分析其对抗菌药物的耐药性,为临床医生合理使用抗菌药物提供依据。方法采用生化酶法检测衣原体,采用培养法检测支原体及其药物敏感试验。结果311例疑似非淋菌性尿道炎(NGU)患者中检出支原体阳性160例,阳性率为51.4%,其中解脲支原体(Uu)阳性率为50.5%(157例),人型支原体(Mh)阳性率0.96%(3例),(Uu+Mh)混合感染率5.46%(17例),检出沙眼衣原体136例,阳性率为43.7%。药敏试验显示:强力霉素、交沙霉素、美满霉素敏感性最高;大观霉素、林可霉素、甲砜霉素,司帕沙星敏感性最低。结论泌尿生殖道感染主要以Uu发病率最高,且耐药株在不断增加,治疗支原体感染应根据药敏结果合理使用抗菌药物。
Objective To observe the infection of mycoplasma and chlamydia in 311 cases of genitourinary tract, analyze the drug resistance to antibiotics, and provide evidences for clinicians to use antibiotics reasonably. Methods Chlamydia was detected by the method of biochemical enzyme. Mycoplasma and its drug sensitivity test were detected by culture method. Results A total of 160 cases of mycoplasma were positive in 311 suspected non-gonococcal urethritis (NGU) patients, with a positive rate of 51.4%. The positive rate of Uu was 50.5% (157 cases), Mycoplasma hominis (Mh) The positive rate was 0.96% (3 cases). The mixed infection rate (Uu + Mh) was 5.46% (17 cases). 136 cases of Chlamydia trachomatis were detected, the positive rate was 43.7%. Drug susceptibility tests showed that: doxycycline, josamycin, minocycline sensitivity; spectinomycin, lincomycin, thiamphenicol, sparfloxacin the lowest sensitivity. Conclusions The highest prevalence of genitourinary tract infection is Uu, and the resistant strains are increasing. The treatment of mycoplasma infection should be based on drug susceptibility results rational use of antimicrobial agents.