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目的:分析呼吸内科住院患者抗菌药物使用的相关因素及其病原学送检率,为抗菌药物临床合理使用提供参考。方法:抽取2016年1—6月间呼吸内科出院患者病历230份,分析抗菌药物合理使用情况。结果:230例病例中使用抗菌药物198例,抗菌药物使用率为86.09%,其中非限制使用级抗菌药物使用率为35.35%,限制使用级抗菌药物使用率为55.56%,特殊使用级抗菌药物使用率为9.09%;抗菌药物使用频度较高的为头孢类和氟喹诺酮类,非限制使用级抗菌药物的DDDs为525.60,限制使用级抗菌药物的DDDs为835.71,特殊使用级抗菌药物的DDDs为51.90;病原学送检率为75.76%,送检阳性率为13.33%。结论:经过抗菌药物专项整治活动后,抗菌药物的使用较为合理,但仍存在一些问题,尚待进一步改进。
OBJECTIVE: To analyze the related factors of antimicrobial use and the rate of etiological examination in hospitalized patients with respiratory medicine, and provide references for clinical use of antimicrobial agents. Methods: Totally 230 medical records of patients discharged from respiratory medicine during January-June 2016 were collected, and the rational use of antibacterials was analyzed. Results: Among the 230 cases, 198 cases were used antibacterial drugs, the antibacterial drug use rate was 86.09%, including 35.35% for non-restricted use antibacterials, 55.56% for restricted use antibacterials, and the use level of special use antibacterials The rate of use of antibacterials was higher for cephalosporins and fluoroquinolones, DDDs for non-restricted use antibacterials was 525.60, DDDs for restricted use antibacterials was 835.71, DDDs for special-use antibacterials were 51.90; the rate of etiological examination was 75.76%, the positive rate of examination was 13.33%. Conclusion: After the anti-bacterial drugs special rectification activities, the use of antimicrobial agents is more reasonable, but there are still some problems to be further improved.