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目的:探讨应用放射性125I粒子组织间植入近距离治疗唾液腺恶性肿瘤的疗效。方法:12例唾液腺恶性肿瘤利用放射性125I粒子组织间植入近距离治疗,其中8例采用手术完整切除+粒子植入,2例为手术部分切除+粒子植入,2例因患者无法耐受手术而单纯粒子植入。结果:随访时间2～36个月,单纯粒子植入治疗组肿瘤明显缩小,部分切除+粒子植入组肿瘤完全消失,手术完整切除+粒子植入组至今未复发。以上患者局部控制率91%。结论:放射性125I粒子组织内植入近距离治疗唾液腺恶性肿瘤疗效肯定,但其远期疗效还有待进一步观察随访。
Objective: To investigate the clinical effect of radioactive 125I seed implantation in the treatment of salivary gland malignant tumors. Methods: Twelve cases of salivary gland malignant tumors were treated with brachytherapy with 125I radioactive seeds. Among them, 8 cases were treated with complete resection and implantation of particles, 2 cases were partial resection and implantation of particles, and 2 cases were unable to tolerate surgery Simple particle implantation. Results: The follow-up time ranged from 2 months to 36 months. The tumors in the simple particle implantation group were significantly reduced. The tumors in the partial resection plus the particle implantation group completely disappeared. The complete resection plus the particle implantation group had not relapsed so far. The local control rate of 91% of patients. CONCLUSION: Radioactive 125I seeds are effective in implanting salivary gland tumors in brachytherapy. However, its long-term efficacy remains to be followed up.