Good综合征(Good syndrome,GS)是一种罕见的合并胸腺瘤的成人原发性免疫缺陷病,典型特征为低丙种球蛋白血症、免疫缺陷合并胸腺瘤~([1]),该病老年人高发,无性别差异,占胸腺瘤患者的10%,其发病机制尚不明确。主要临床表现为自身免疫性疾病合并反复机会性感染,特别是含荚膜细菌的感染,肺部为最常受累部位。郑州大学第一附属医院 Good syndrome (GS) is a rare adult primary immunodeficiency disease with thymoma. It is typically characterized by hypogammaglobulinemia, immunodeficiency associated with thymoma ~ ([1]) High incidence of the elderly, no gender differences, accounting for 10% of thymoma patients, the pathogenesis is not yet clear. The main clinical manifestations of autoimmune diseases combined with recurrent opportunistic infections, especially with capsular bacterial infections, the lungs are the most commonly involved sites. First Affiliated Hospital of Zhengzhou University