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小肠血管床对循环内稳态的维持有着重要影响,休克时的缺血小肠对休克不可逆发展起了很重要的作用。本工作在家兔失血性休克模型上,观察影响小肠功能及结构的各因素-肠腔温度,渗透压、胀气,炎症等对休克过程的影响。 局麻下肠道造瘘,按不同分组向肠腔灌注不同物质,15分钟后从股动脉放血进入贮血器,到血压40mm Hg,代偿期内血液不断进入贮血器,失代偿后血液不断输回机体,以维持血压于40mm Hg 2小时。然后将贮血器里全部剩余的放出血液由股静脉输回。输血毕后2小时结束实验。分组:1)对照
Intestinal vascular bed on the steady-state maintenance of circulation has an important impact, the ischemic intestine in shock when the irreversible development of shock plays a very important role. This work in rabbits hemorrhagic shock model, observe the factors that affect the small bowel function and structure - intestinal lumen, osmotic pressure, flatulence, inflammation and other shock process. Local anesthesia under the intestinal fistula, different groups according to the intestinal perfusion of different substances, 15 minutes after the bleeding from the femoral artery into the blood reservoir, to the blood pressure 40mm Hg, compensatory period of blood into the blood reservoir, decompensated blood Continue to lose body weight to maintain blood pressure at 40 mm Hg for 2 hours. Then all the remaining blood in the reservoir is released from the femoral vein. 2 hours after the end of transfusion experiment. Grouping: 1) Control