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该文旨在系统回顾1999-2008年间头颈鳞癌(HNSCC)患者,并对其肺转移的临床预测指标进行评估。结果:纳入研究的428例患者,平均随访65个月。80(18.6%)例患者出现了肺转移。多因素回归分析显示,局部复发与吸烟是与肺转移相关的高危因素(P<0.001和P=0.008)。结论:HNSCC患者局部复发和长期吸烟史是肺转移的预测指标。
This article aims to systematically review patients with head and neck squamous cell carcinoma (HNSCC) from 1999 to 2008 and evaluate their clinical predictors of lung metastases. Results: 428 patients enrolled in the study were followed up for an average of 65 months. 80 (18.6%) patients had lung metastases. Multivariate regression analysis showed that local recurrence and smoking were risk factors for lung metastases (P <0.001 and P = 0.008). Conclusions: Local recurrence and long-term smoking history in patients with HNSCC are predictors of lung metastasis.