各种造血细胞的终末分化是组织特异性基因产物协同配合作用的结果 ,该现象部分是由基因转录水平进行调节的。GATA- 1是红系特异谱系转录因子 ,红系基因的表达在其控制之下。近年来 ,又发现 GATA- 1也是巨核细胞系、肥大细胞系分化发育 ,基因表达的重要调控因子。本文仅就 GATA- The terminal differentiation of various hematopoietic cells is the result of the synergistic effect of tissue-specific gene products, which is partly regulated by the level of gene transcription. GATA-1 is an erythroid lineage transcription factor, and the expression of the erythroid gene is under its control. In recent years, it has also been found that GATA-1 is also an important regulatory factor for gene expression in the development of megakaryocytic and mast cell lines. This article is only about GATA-