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目的了解广东梅州市大埔、平远和梅县莱姆病人群血清流行病学、动物宿主和传播媒介特征。方法应用间接免疫荧光试验(IFA)和酶联免疫吸附试验(ELISA)进行人群和宿主动物的血清学检测、个案调查、动物宿主和传播媒介病原学调查。结果检测人群血清2 184份,莱姆病感染率为10.30%(225/2184),其中林区为10.33%(123/1191),非林区为10.27%(102/993),差异无统计学意义(χ2=0.21,P>0.5);检测牛和野鼠血清各30份,感染率分别为23.33%和43.33%;从褐家鼠和白腹巨鼠各分离到1株莱姆病螺旋体;调查蜱506只,其中台湾角血蜱493只,占97.43%,该蜱中肠带莱姆病螺旋体率为16.00%(8/50),且分离到1株莱姆病螺旋体。结论梅州市存在莱姆病自然疫源地,人群普遍易感,野鼠和牛是该地莱姆病螺旋体的主要动物宿主,台湾角血蜱是主要传播媒介。
Objective To understand the serum epidemiology, animal host and vector characteristics of Lyme disease in Dapu, Pingyuan and Meixian, Meizhou, Guangdong Province. Methods Serological test, case investigation, animal host and vector pathogen investigation were conducted in both population and host animals using indirect immunofluorescence assay (IFA) and enzyme-linked immunosorbent assay (ELISA). Results A total of 2 184 serum samples were collected and the infection rate of Lyme disease was 10.30% (225/2184), with 10.33% (123/1191) in forest area and 10.27% (102/993) in non-forest area, the difference was not statistically significant (Χ2 = 0.21, P> 0.5). The detection rates of serum and serum of cattle and wild rats were 30 and 23.33%, respectively, and 43.33% respectively. One strain of Borrelia burgdorferi There were 506 ticks, accounting for 97.43% of the total, accounting for 16.00% (8/50) of the total Lyme disease in the tick, and one strain of Lyme disease was isolated. Conclusion Meizhou City is a natural epidemic area of Lyme disease, and the population is generally susceptible. Vole and cattle are the major animal hosts for this Lyme disease spirochete, and H. xylostellas is the main transmission medium.