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观察了28例Ⅱ期高血压病患者平均口服依那普利平均22个月后左室结构及功能改变。结果显示：用药后血压降低总有效率为89．3％，心率无变化。用药后空间隔、左室后壁及左定重量指数均明显下降（P＜0．05），A峰速度及A／E比值明显下降，E峰速度明显增高（P＜0．05）。提示：依那曾利长期治疗可有效降压，并同时逆转左室肥厚，改善左室舒张功能。
The changes of left ventricular structure and function were observed after the mean oral enalapril treatment in 28 patients with stage II essential hypertension. The results showed that: the total effective rate of blood pressure decreased 89.3%, no change in heart rate. After treatment, the space interval, left ventricular posterior wall and left fixed weight index decreased significantly (P <0.05), A peak velocity and A / E ratio decreased significantly, E peak velocity increased significantly (P <0.05). Tip: According to that long-term treatment can be effective antihypertensive, and at the same time reverse left ventricular hypertrophy and improve left ventricular diastolic function.