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目的探讨华法林在房颤中的应用。方法对本院120例患者的临床疗效进行分析。结果2例有并发出血,其中1例为严重出血,经抢救无效死亡,当时测INR为2.7;1例轻度出血当时测INR为3.5,经停用2d后华法林减量为2.0mg后维持INR为2.0水平,无进一步出血。腔隙性脑梗死1例,周围血栓栓塞1例。结论适量华法林用于房颤的抗凝治疗是安全可靠的,无严重出血并发症,抗凝效果好,值得临床推广使用。
Objective To investigate the application of warfarin in atrial fibrillation. Methods The clinical efficacy of 120 patients in our hospital was analyzed. Results Two patients had concurrent hemorrhage, of which 1 was severe bleeding and died after rescue operation. At that time, the INR was 2.7. At 1 month, mild bleeding was measured with an INR of 3.5. After 2 days of withdrawal, warfarin was reduced to 2.0 mg INR was maintained at a level of 2.0 with no further bleeding. 1 case of lacunar infarction and 1 case of peripheral thromboembolism. Conclusion The appropriate amount of warfarin for atrial fibrillation anticoagulant therapy is safe and reliable, no serious bleeding complications, anticoagulant effect is good, worthy of clinical promotion and use.