论文部分内容阅读
目的分析急诊内科肺炎克雷伯菌引发肺部感染患者的用药情况,为患者临床治疗及合理用药提供指导。方法选取本院339例肺部感染肺炎克雷伯菌的急诊内科患者,进行患者感染疾病类型分析及用药情况分析。结果门诊患者数共3 148例,取其中1 285例患者痰检样本作为标本,样本构成情况分别为呼吸系统(肺部感染)79.08%、消化系统40.09%、全身39.05%、泌尿生殖系统30.33%、皮肤30.26%、传染病27.52%、结核病20.56%、神经系统16.50%、其他类型28.24%。通过痰检确定感染肺炎克雷伯菌阳性的患者数为339例,其中呼吸系统(肺部感染)感染患者占31.86%、消化系统患者占19.76%、全身患者占15.63%、泌尿生殖系统患者占10.32%、皮肤患者占7.08%、传染病患者占5.90%、结核病患者占2.65%、神经系统患者占1.47%、其他类型患者占5.31%。进一步研究患者感染药物使用情况发现,本院急诊内科常用抗菌药物包括头孢类、大环内酯类、喹诺酮类、青霉素类、氨基糖苷类、四环素类、硝基咪唑类、合并用药类及其他种类抗生素,相应抗菌药物所占比例依次为26.84%、20.94%、18.29%、8.85%、8.85%、5.01%、4.13%、3.24%和3.83%。药敏实验结果显示,肺炎克雷伯菌对头孢类、大环内酯类、喹诺酮类、青霉素类、氨基糖苷类、四环素类以及硝基咪唑类均产生了耐药性,这一结果患者用药情况相符。结论急诊内科肺炎克雷伯菌引发肺部感染情况广泛分布于各类疾病患者中。常用治疗药物包括头孢类、大环内酯类、喹诺酮类、青霉素类、氨基糖苷类、四环素类、硝基咪唑类、合并用药类及其他种类抗生素,且使用情况各不相同,并且肺炎克雷伯菌的耐药情况与患者的临床用药情况相符。
Objective To analyze the medication situation of patients with pulmonary infection caused by Klebsiella pneumoniae in emergency department and provide guidance for clinical treatment and reasonable medication. Methods A total of 339 patients with Klebsiella pneumoniae pneumonia in our hospital were enrolled in this study. The types of patients infected with the disease and their medication were analyzed. Results A total of 3 148 outpatients were enrolled in this study. Among them, 1 285 cases of sputum samples were taken as samples. The samples consisted of 79.08% of the respiratory system (pulmonary infection), 40.09% of the digestive system, 39.05% of the whole body and 30.33% of the genitourinary system , Skin 30.26%, infectious disease 27.52%, tuberculosis 20.56%, nervous system 16.50%, other types of 28.24%. The number of sputum positive Klebsiella pneumoniae patients was 339, of which 31.86% were respiratory system infection (pulmonary infection), 19.76% were digestive system diseases, 15.63% were systemic diseases, and genitourinary system accounted for 10.32%, skin patients accounted for 7.08%, infectious diseases accounted for 5.90%, tuberculosis accounted for 2.65%, nervous system patients accounted for 1.47%, other types of patients accounted for 5.31%. To further study the use of patients infected with drugs found that the hospital emergency medicine commonly used antibacterial drugs, including cephalosporins, macrolides, quinolones, penicillins, aminoglycosides, tetracyclines, nitroimidazoles, combined with drugs and other types The proportions of antibiotics and corresponding antimicrobial agents were 26.84%, 20.94%, 18.29%, 8.85%, 8.85%, 5.01%, 4.13%, 3.24% and 3.83%, respectively. The result of drug susceptibility test showed that Klebsiella pneumoniae developed drug resistance to cephalosporins, macrolides, quinolones, penicillins, aminoglycosides, tetracyclines and nitroimidazoles, and the patients were treated with the drug The situation is consistent. Conclusions Emergency medical department Klebsiella pneumoniae caused pulmonary infection is widely distributed in patients with various diseases. Commonly used therapeutic drugs include cephalosporins, macrolides, quinolones, penicillins, aminoglycosides, tetracyclines, nitroimidazoles, combination medication and other types of antibiotics, and the use of different, and pneumococcal The resistance of the bacteria is consistent with the patient’s clinical medication.