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目的探讨冠心病患者无创平板运动试验Duke评分(DTS)与冠状动脉造影评价预后的指标校正的TIMI帧数(CTFC)之间的相关性,为利用无创的平板运动试验评价冠心病患者的预后提供依据。方法对冠状动脉造影确诊为冠心病,并在造影前2周内完成平板运动试验的患者61例进行回顾性分析。根据DTS进行分组(≥5分为低危组、<5分为中高危组),分析DTS与CTFC的相关性,比较不同危险组间CTFC的差异。结果DTS与冠心病患者冠状动脉前降支(LAD)、回旋支(LCX)、右冠状动脉(RCA)的CTFC均呈负相关(r=-0·834、-0·769、-0·698,均P<0·01)。DTS低危组3支冠状动脉的CTFC值明显小于中高危组,组间CTFC值有明显差异[LAD:(21·3±1·7)帧vs(24·1±2·2)帧;LCX:(26·9±2·6)帧vs(30·6±3·4)帧;RCA:(21·1±4·0)帧vs(25·1±4·3)帧,均P<0·01]。结论冠心病患者平板运动试验Duke评分与LAD、LCX、RCA的CTFC值呈负相关。根据DTS得出的危险分层与CTFC有良好的相关性。
Objective To investigate the correlation between Duke score (DTS) of noninvasive treadmill exercise test in patients with coronary heart disease and the corrected TIMI frames (CTFC) after coronary angiography. To evaluate the prognosis of patients with coronary heart disease by noninvasive treadmill exercise test in accordance with. Methods Coronary angiography was diagnosed as coronary heart disease, and 61 cases of treadmill exercise test within 2 weeks before angiography were retrospectively analyzed. According to DTS grouping (≥5 points into low risk group, <5 points for middle and high risk group), the correlation between DTS and CTFC was analyzed, and CTFC differences among different risk groups were compared. Results DTS was negatively correlated with CTFC of coronary anterior descending coronary artery (LAD), circumflex artery (LCX) and right coronary artery (RCA) in patients with coronary heart disease (r = -0.834, -0.769, -0.698 , All P <0.01). The CTFC values of three coronary arteries in DTS low-risk group were significantly lower than those in middle-high risk group, with significant differences in CTFC values between groups [LAD: (21.3 ± 1.7) frames vs (24.1 ± 2.2) frames; LCX : (26.9 ± 2.6) frames vs (30.6 ± 3.4) frames; RCA: (21.1 ± 4.0) frames vs (25.1 ± 4.3) frames with P < 0 · 01]. Conclusion The Duke score of treadmill exercise test in patients with coronary heart disease was negatively correlated with CTFC values of LAD, LCX and RCA. The risk stratification based on DTS has a good correlation with CTFC.