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目的：观察苯黄粉剂（Ａ）和华素片（Ｂ）对急性高原性口腔溃疡的治疗效果。方法：对进驻５２００ｍ高原的１２０名部队健康青年进行口腔溃疡病流行病学调查，对诊断为首次患口腔溃疡病的５７名患者，随机分组进行药物治疗。Ａ组３７名，将黄连素、苯妥英钠各半片混合碾磨成粉，均匀撒于略大于溃疡面的棉片上，然后贴于患处，约３０分钟后取出，１／ｄ。Ｂ组２０名，每次含化１片，１／ｄ。结果：Ａ组治愈率为９４．８６％，Ｂ组治愈率为６５％，两组治疗效果比较有非常显著的差别（Ｐ＜０．０１）。１０例复发型溃疡病患者的治疗，首先用Ｂ治疗，无效后改用Ａ治疗，前者治愈率为２０％，后者为８５．６％，两组治疗效果比较Ａ明显优于Ｂ（Ｐ＜０．０５）。结论：苯黄粉剂治疗急性（或慢性）高原性口腔溃疡病的效果明显优于华素片，用量小，无毒副作用，药源广，适用于高原基层医疗单位配制使用，是治疗急性高原性口腔溃疡的有效方法，同时对该病流行病学、发病因素进行了阐述
OBJECTIVE: To observe the therapeutic effect of PTS (A) and Hua-Hua Pian (B) on acute high-altitude oral ulcer. Methods: An epidemiological investigation of oral ulcer disease was conducted in 120 army healthy young people stationed at 5200m plateau. 57 patients with oral ulcer disease diagnosed for the first time were randomly assigned to receive drug treatment. A group of 37, the berberine, phenytoin each half of the tablets were mixed and ground into powder, evenly sprinkled on the cotton sheet slightly larger than the ulcer surface, and then affixed to the affected area, about 30 minutes after the removal, 1 / d. B group of 20, each containing 1, 1 / d. Results: The cure rate of group A was 94.86%, while that of group B was 65%. There was a significant difference between the two groups (P <0.01). 10 cases of patients with recurrent ulcer disease treatment, first with B treatment, switch to A after treatment ineffective, the former cure rate was 20%, the latter 85.6%, the two groups were significantly better than the treatment A (P < 0.05). Conclusion: The effect of benzene yellow powder in the treatment of acute (or chronic) plateau oral ulcer disease is better than that of Hua Slice. The dosage is small, non-toxic side effects, wide source of medicine, and is suitable for the formulation and use of plateau primary medical units. Oral ulcer effective method, at the same time, the disease epidemiology, the incidence of factors are described