N- D-核糖醇基 - 3,4-二甲苯胺 (1 )是化学合成维生素 B2 (VB2 )的关键中间体[1,2 ] 。 1的合成方法较多 ,但通常是在催化剂和一定氢压下 ,以甲醇或乙醇为溶剂 ,使 4-硝基邻二甲苯或 3,4-二甲苯胺与 D-核糖 (2 )发生反应制得的 [3 ,4 ]。在这些合成方法中 ,所使用的 2均是价昂 N-D-Ribitol-3,4-dimethylaniline (1) is a key intermediate in the chemical synthesis of vitamin B2 (VB2) [1,2]. 1 synthesis method is more, but usually under the catalyst and a certain hydrogen pressure, methanol or ethanol as a solvent, 4-nitro-o-xylene or 3,4-dimethylaniline and D-ribose (2) reacts Prepared [3, 4]. In these synthetic methods, the 2 used are expensive