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为了探讨日本棘隙吸虫病的治疗药物与方案,我们对50例粪检阳性病例采用吡喹酮进行治疗观察。50例分层随机抽样分为3组,分别给予吡喹酮20、10、5mg/kg顿服,各15、17和17例,另2mg/kg1例。上述3组治后1月粪检阴转率依次为86.7％(13/15)、94.1％(16/17)和100％(17/17):经统计学处理,3组间无显著差异(P>0.05)。2mg/kg者治后1月粪检仍阳性,但大便虫卵较治前减少94.4％。结果表明,吡喹酮是治疗该病的有效药物,药物副作用较轻,疗效较好,给药简便。建议在实际应用中采用5～10mg/kg顿服进行治疗。
In order to explore the treatment of Japanese echinococcosis drugs and programs, we used 50 cases of positive fecal seizures treated with praziquantel. Fifty patients were randomly divided into three groups. Patients were treated with praziquantel 20, 10, 5 mg / kg, 15, 17, and 17 cases respectively, and the other 2 mg / kg in 1 case. The negative rates of feces and urine tests in the three groups after January 1 were 86.7% (13/15), 94.1% (16/17) and 100% (17/17) respectively. There was no significant difference among the 3 groups P> 0.05). 2mg / kg after treatment in January was still positive stool test, but the stool egg decreased 94.4% compared with the pre-treatment. The results showed that praziquantel is an effective drug for the treatment of the disease with less side effects and better curative effect. Recommended in the practical application of 5 ~ 10mg / kg Dayton clothing for treatment.