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目的探讨病灶刮除、蒸馏水+氯化锌灭活、抗菌素骨水泥填充、钢板螺钉内固定手术方法治疗临近膝关节CampanacciⅢ级骨巨细胞瘤的有效性。方法回顾分析2004年3月至2009年11月收治的13例临近膝关节CampanacciⅢ级骨巨细胞瘤患者,入院后均经病理活检确诊后采取上述手术方法治疗。所有患者均获得随访,随访时间1.5-7.2年,平均随访5.1年。随访时评估受试者HSS评分、VAS评分及影像学资料评估。结果所有患者术后均未发现复发,无骨水泥及内固定失效问题,且HSS评分、VAS评分较术前明显改善。结论病灶刮除、瘤壁蒸馏水+氯化锌灭活、抗菌素骨水泥填充、钢板螺钉内固定是治疗临近膝关节CampanacciⅢ级骨巨细胞瘤的一种有效、复发率较低的手术方法 。
Objective To investigate the effectiveness of lesion curettage, distilled water + zinc chloride inactivation, antibiotic bone cement filling, and plate screw fixation in the treatment of Campanacci grade III giant cell tumor near knee joint. Methods A retrospective analysis of 13 cases of patients with giant cell tumor of Campanacci Ⅲ, who were admitted to our hospital from March 2004 to November 2009, was admitted to our hospital for pathological biopsy. All patients were followed up for 1.5-7.2 years with a mean follow-up of 5.1 years. Subjects were assessed for HSS score, VAS score, and imaging data at follow-up. Results All patients had no recurrence after operation, no bone cement and internal fixation failure problems, and HSS score, VAS score significantly improved compared with preoperative. Conclusion Scraping of lesions, inactivation of tumor wall distilled water + zinc chloride, antibiotic cement and screw fixation are effective and low recurrence rates for the treatment of Campanacci grade III giant cell tumor in the knee.