勾端螺旋体病肺弥蔓性出血(以下简称勾体病肺弥蔓性出血,过去称为肺大出血)临床显著特点是发生突然、发展迅猛,临终多数患者出现从口鼻喷出大量血液(以下简称口鼻涌血)、病人立即窒息而死。我院曾作了一些初步研究,但口鼻涌血的病理本质和发病因素迄今未获阐明,为了进一步探讨勾体病肺弥蔓性出血的发病原理,我们进行了以下实验性研究。 Leptospirosis pulmonary diffuse mucosal bleeding (hereinafter referred to as hook disease diffuse pulmonary hemorrhage, formerly known as pulmonary hemorrhage) clinically significant feature is the sudden, rapid development, the majority of patients died from the nose and mouth spurt a lot of blood (below Referred to as mouth and nose blood flow), the patient died of suffocation immediately. Our hospital had made some preliminary studies, but the nature of the pathology and pathogenesis of buxom blood has not been clarified so far, in order to further explore the pathogenesis of hook disease pulmonary diffuse hemorrhage, we conducted the following experimental study.