肝素是由2-氨基-2-脱氧-D-葡萄糖和α-D-葡萄糖醛酸通过1—4糖甙键连接起来的局部硫酸酯化的粘多糖。广泛存在于许多动植物体内,其中牛肺、猪、羊的小肠粘膜中含量极为丰富。对于肝素的早期历史,化学和临床应用,许多研究工作者已作了阐述,对于肝素的一般理化性质和药理学也有专述。因为肝素有明显的抗凝血作用,目前广泛应用于预防和治疗心血管外科手术后引起的动脉血栓、肺血栓、静脉血栓、周围血管 Heparin is a locally sulphated mucopolysaccharide linked by 1-4 glycosidic bonds between 2-amino-2-deoxy-D-glucose and alpha-D-glucuronic acid. Widely existing in many plants and animals, including bovine lungs, pigs, sheep, the intestinal mucosa content is extremely rich. For the early history, chemistry and clinical application of heparin, many researchers have elaborated on the general physical and chemical properties and pharmacology of heparin. Because of heparin obvious anticoagulant effect, is currently widely used in the prevention and treatment of cardiovascular surgery caused by arterial thrombosis, pulmonary thrombosis, venous thrombosis, peripheral blood vessels