Charcot-Marie-Tooth 病是以下肢远端和手部肌肉萎缩、感觉障碍、畸形足、仙鹤腿和足下垂为其特征.本文报导一例Charcot-Marie-Tooth 病的典型病例。患者男性,32岁.数年来渐感双下肢进行性无力,尤以膝以下为甚.一年前感觉在进行细微动作时较困难,右上肢功能障碍较左上肢严重。患者有明显家族史。检查见双踝仅能中度背屈,外翻时肌力减退,肢体活动范围正常,双上肢肌肉明显萎缩.拇短展 Charcot-Marie-Tooth disease is characterized by muscle atrophy, sensory disturbances, deformities, crane legs and ptosis in the distal and extremities of the lower limbs.This article reports on a typical case of Charcot-Marie-Tooth disease. The patient, male, was 32. Over the years, her lower extremities became gradually weak, especially below the knees, feeling more difficult a year ago than before, and having a right upper extremity dysfunction worse than her left upper extremity. Patients have a clear family history. Check see the double ankle can only moderate dorsiflexion, valgus when the strength loss, physical range of normal limbs, both upper extremity muscles significantly atrophy.