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本实验对肺弥漫性间质性疾病(PDID)26例(实验组)和肺局限性疾病9例(对照组)的支气管肺泡灌洗(BAL)液进行了细胞学及生化学的研究。结果表明PDID患者BAL液中炎症细胞及免疫效应细胞显著增多,且分类有显著差异;IgG、溶菌酶、纤维结合蛋白显著增加;血管紧张素转换酶在结节病显著增加。我们认为BAL为PDID的诊断及病理机制的研究提供了一种较为有效的方法。
In this study, cytology and biochemistry of bronchoalveolar lavage (BAL) fluid in 26 patients with diffuse interstitial lung disease (PDID) and 9 patients with localized pulmonary disease (control group) were studied. The results showed that the inflammatory cells and immune effector cells in BAL fluid of PDID patients were significantly increased, and the classification was significantly different; IgG, lysozyme, fibronectin increased significantly; angiotensin converting enzyme increased significantly in sarcoidosis. We think that BAL provides a more effective method for the study of PDID diagnosis and pathological mechanism.