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目的探讨新生儿呼吸道合胞病毒(RSV)肺炎的临床特点,以指导临床对新生儿RSV感染进行有效的防治。方法对46例新生儿RSV肺炎的临床资料进行回顾性分析。结果本组患儿足月儿38例(82.6%),早产儿8例(17.4%);发病年龄以21～28d居多33例(71.7%);混合和人工喂养为主36例(78.3%);临床表现以咳嗽、气促、喘憋、肺部湿性啰音及喘鸣音,x线胸片肺气肿、条索状或小片状阴影为主,合并心力衰竭8例;呼吸衰竭10例;经对症支持、抗感染等综合治疗,43例治愈出院,3例好转后自动出院;平均住院13d。结论新生儿呼吸道合胞病毒肺炎随日龄增加感染机会增多,临床表现缺乏特异性。在RSV高发季节,警惕RSV感染,及时进行特异性病原学诊断对防范隔离及合理用药十分重要。
Objective To explore the clinical features of neonatal respiratory syncytial virus (RSV) pneumonia and to guide clinical prevention and treatment of neonatal RSV infection. Methods The clinical data of 46 neonates with RSV pneumonia were retrospectively analyzed. Results The full-term infants had 38 cases (82.6%) in full-term infants and 8 (17.4%) premature infants. The age of onset was mostly in 21 ~ 28 days (71.7%), mixed and artificial feeding was in 36 cases ; Clinical manifestations of cough, shortness of breath, wheezing, lung wet rales and wheezing, x-ray chest emphysema, cord-like or small shadows, with heart failure in 8 cases; respiratory failure 10 Cases; After symptomatic support, anti-infective and other comprehensive treatment, 43 cases were cured and discharged, 3 cases were automatically discharged after improvement; The average hospitalization 13d. Conclusion Neonatal respiratory syncytial virus pneumonia increased with the increasing of age, the clinical manifestations of the lack of specificity. In the high season of RSV, it is very important to guard against RSV infection and promptly conduct specific etiological diagnosis to prevent isolation and rational drug use.