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为研究刺激性接触性皮炎的发病机理,作者用2%SLS(十二烷基磺酸钠)对11名健康女性(年龄在18～72岁之间,平均47.4岁)进行了重复斑贴试验,并通过肉眼观察、表皮水份丧失及激光多普勒速度测量计对其结果进行了评价。方法:11名受试者,共在34个部位进行斑试。其中5名受试者,每人在左前臂屈侧及背部左侧,6名受试者每人在双前臂屈侧和背部两侧进行。第一天,将2%SLS于34个部位进行闭合斑试,24小时去掉斑试物,标明受
To study the pathogenesis of irritant contact dermatitis, the authors performed repeat patch tests on 11 healthy women (aged 18-72 years, mean 47.4 years) with 2% SLS (sodium dodecyl sulfate) The results were evaluated by visual inspection, loss of epidermis water, and laser Doppler velocimetry. METHODS: Eleven subjects underwent a plaque test in 34 sites. Five of the subjects, each on the left forearm flexion and on the left back, six subjects each performed on the flexor and back of both forearms. The first day, 2% SLS closed plaque test in 34 parts, 24 hours to remove plaque test, marked by