[Objective]To detect the optimal condition for the supercritical CO2extraction of volatile oil from RADIX ET RHIZOMA GINSENG.[Methods]The single factor test and orthogonal test on the extraction of volatile oil from RADIX ET RHIZOMA GINSENG were carried out by supercritical CO2extraction.The extraction technology was researched;and the effects of extraction pressure,extraction temperature,extraction time and CO2flow rate on the extraction rate of volatile oil were investigated.[Results]The optimal condition for the supercritical extraction of volatile oil from RADIX ET RHIZOMA GINSENG was as follows:30 MPa extraction pressure,40℃extraction temperature,100 min extraction time,and 25-30 L/h CO2flow rate.[Conclusions]Under this extraction condition,the extraction rate of volatile oil(crude oil)from RADIX ET RHIZOMA GINSENG was 0.880%,which was far higher than that by the traditional Soxhlet extraction method. [Objective] To detect the optimal condition for the supercritical CO2 extraction of volatile oil from RADIX ET RHIZOMA GINSENG. [Methods] The single factor test and orthogonal test on the extraction of volatile oil from RADIX ET RHIZOMA GINSENG were carried out by supercritical CO2 exclusion. extraction technology was researched; and the effects of extraction pressure, extraction temperature, extraction time and CO2flow rate on the extraction rate of volatile oil were investigated. [Results] The optimal condition for the supercritical extraction of volatile oil from RADIX ET RHIZOMA GINSENG was as [Conclusions] Under this extraction condition, the extraction rate of volatile oil (crude oil) from RADIX ET RHIZOMA GINSENG was 0.880%, which was far higher than that by the traditional Soxhlet extraction method.