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《JAMA》1983;250(4):459. 阿霉素盐酸盐和柔毛霉素盐酸盐是抗癌药物中两种最强的药,除对骨髓有抑制作用外,两种均有心脏毒性的严重副作用,有时可以致死。然而,最近有些研究所已开始研制一些方法来消除以上的弊端,以便增强治疗过程中药的效力。加利福尼亚门洛帕克的国际斯坦福研究所(SRI)和俄亥俄达布林的艾德里实验室的研究人员制造出一种阿霉素衍生物,似乎较母质
JAMA 1983; 250(4): 459. Doxorubicin hydrochloride and daunorubicin hydrochloride are the two most powerful drugs in anticancer drugs. In addition to their inhibitory effects on bone marrow, both have Serious side effects of cardiotoxicity can sometimes be fatal. However, some research institutes have recently started to develop methods to eliminate the above drawbacks in order to enhance the effectiveness of traditional Chinese medicine in the treatment process. Researchers at the International Stanford Research Institute (SRI) in Menlo Park, Calif., and Atelier Laboratories in Dabrin, Ohio, manufactured a doxorubicin derivative that appears to be more potent than parent materials.