单核细胞增生李斯特菌(Listeria monocytogenes)能引起人和动物脑膜炎、败血症、流产和单核细胞增多等症状,临床发病率在美国和欧洲等西方发达国家大约为2 8例/10万人,死亡率20%30%或更高,被WHO列为关系食品卫生安全的重要病源细菌之一[1 2]。该菌能在多数固体表面形成生物被膜,在食品生产、加工、 Listeria monocytogenes can cause meningitis, septicemia, abortion and mononucleosis in humans and animals. The clinical incidence is about 28 cases / 100000 in developed countries such as the United States and Europe , Mortality 20% 30% or more, is listed by WHO as one of the important pathogens that affect food hygiene and safety [1 2]. The bacteria in the majority of solid surface biofilm formation, in food production, processing,