目的:对高危妊娠药流联合无痛清宫术的安全性进行探讨。方法:选取我站确诊为宫内妊娠且存在高危因素的180例患者,对该类患者采用米非司酮伍米索前列醇终止早妊,行无痛清宫术。并对安全性进行观察评估。结果:实施药流及无痛清宫术后,完全流产率及不完全流产率分别为97.78%和2.22%,无流产失败。平均阴道出血时间、平均阴道出血量、平均腹痛时间和总不良反应发生率分别为3.55±2.31min,30.30±2.06ml,4.61±0.32min,5.01%。结论:对高危妊娠孕妇实施药流联合无痛清宫术的方式干预,能够取得较好的安全性效果,阴道出血及腹痛时间均较短,出血量也较少,不良反应轻微且发生率较低,值得基层医疗单位推广应用。 Objective: To investigate the safety of painless hysteroscopic surgery in high-risk pregnancy. Methods: One hundred and eighty patients with intrauterine pregnancy who were diagnosed as intrauterine pregnancies with high risk factors were selected. Mifepristone and mifepristone were used to terminate early pregnancy and painless hysterisis. And observe and evaluate the safety. Results: The rate of complete abortion and incomplete abortion were 97.78% and 2.22% respectively after abortion and painless curettage, with no abortion. The mean vaginal bleeding time, average vaginal bleeding volume, average abdominal pain time and total adverse reactions were 3.55 ± 2.31min, 30.30 ± 2.06ml, 4.61 ± 0.32min, 5.01% respectively. Conclusion: Interventions of medical abortion and painless hysteroscopy in high-risk pregnant women can achieve better safety effect, shorter duration of vaginal bleeding and abdominal pain, less amount of bleeding, mild adverse reactions, and lower incidence of adverse reactions. It is worth to promote the application of primary medical units.