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作者根据在不同的脑区神经元中含有不同浓度的胰岛素提出一可能的假设,即这种激素也作用于中枢神经系统神经元的识别点,以调节由特异性神经递质唤起的神经元兴奋性.从已有的资料来看,脑内胰岛素作为附递质或者一种神经调制物的可能性不能排除.作者观察到行单侧嗅球切除后的对侧嗅球切片,胰岛素或多巴胺可使CAMP水平明显升高.将胰岛素与多巴胺同时加入切片,则胰岛素能抑制多巴胺升高CAMP含量的作用,这种抑制作用似乎是G_(pp) NH_p依赖性的.我们不知道胰岛素与多巴胺的互相作用是否涉及到多巴胺受体积极地(positively)或消极地(negatively)与腺苷酸环化酶结合.事实上,胰岛素能释放另一种递质,后者进一步以积极或消极
The authors propose a possible hypothesis based on the fact that different concentrations of insulin are contained in different brain regions of the neurons that act on the recognition of neurons in the central nervous system to regulate excitability of neurons elicited by specific neurotransmitters From the available data, the possibility of intracerebral insulin as a neurotransmitter or neurotransmitter can not be ruled out. The authors observed that unilateral olfactory bulb after excision of the contralateral olfactory bulb, insulin or dopamine can CAMP The level was significantly increased.Collecting insulin and dopamine at the same time, then insulin can inhibit dopamine increase CAMP content, this inhibition appears to be G_ (pp) NH_p dependent.We do not know whether the interaction of insulin and dopamine is Involves the dopamine receptor positively or negatively associated with adenylate cyclase.In fact, insulin can release another neurotransmitter, the latter further positive or negative