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目的调查农村基层医疗卫生人员乙型肝炎病毒感染现状,采取行之有效的预防乙型肝炎病毒感染的措施。方法采用酶联免疫吸附试验(ELISA)检测农村基层医疗卫生工作人员血清中的HBsAg、HBeAg、抗-HBs、抗-Hbe含量。结果农村基层医疗卫生工作人员HBsAg总阳性率为3.33%。临床科组人员与非临床科组人员的阳性率分别为4.90%和1.85%,两组间差异有统计学意义(P<0.05)。临床科组与非临床科组的抗-HBs阳性率分别为93.63%和91.67%,且临床科组与非临床科组的HbeAg、抗-HBe和抗-HBc总阳性率分别为2.38%、2.14%和2.38%,两组间差异均无统计学意义(P>0.05)。结论农村基层医疗卫生工作人员乙型肝炎病毒感染率临床科组较非临床科组高。基层医疗卫生人员虽有防病意识,但因职业因素,更应采用加强自我保护、规范临床操作、做好消毒工作、接种乙型肝炎疫苗等综合性预防措施控制乙型肝炎病毒感染。
Objective To investigate the current status of hepatitis B virus infection among rural primary health care workers and to take effective measures to prevent hepatitis B virus infection. Methods Serum HBsAg, HBeAg, anti-HBs and anti-HBe were detected by enzyme-linked immunosorbent assay (ELISA) in rural primary health care workers. Results The total positive rate of HBsAg in rural primary health care workers was 3.33%. The positive rates of clinical subjects and non-clinical subjects were 4.90% and 1.85%, respectively, with significant difference between the two groups (P <0.05). The positive rates of anti-HBs in clinical and non-clinical subjects were 93.63% and 91.67% respectively, and the positive rates of HbeAg, anti-HBe and anti-HBc in clinical and non-clinical subjects were 2.38% and 2.14 % And 2.38% respectively. There was no significant difference between the two groups (P> 0.05). Conclusion The prevalence of hepatitis B virus infection in primary health care workers in rural areas is higher than that in non-clinical subjects. Although grass-roots medical and health personnel have awareness of disease prevention, due to occupational factors, more comprehensive prevention measures such as strengthening self-protection, standardizing clinical practice, performing disinfection work, and inoculating hepatitis B vaccine should be adopted to control the hepatitis B virus infection.