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目的探讨高血压个体脑卒中与左心室肥厚的关系。方法比较易卒中型肾血管性高血压大鼠发生与未有脑卒中的血压水平及左心室肥厚程度，观察经１０周抗高血压后，其脑卒中与血压和左心室肥厚的关系。结果脑卒中大鼠的血压水平及左心室肥厚程度比未卒中者更高。抗高血压后期，其血压水平与高血压对照组无显著性差异，但随着左心室肥厚的减轻，脑卒中率显著降低。结论左心室肥厚和脑卒中均为高血压的并发症，而前者不是后者的独立危险因素。减轻左心室肥厚的抗高血压治疗，即使降血压轻微，对预防脑卒中仍有意义
Objective To investigate the relationship between stroke and left ventricular hypertrophy in hypertensive individuals. Methods Compared the blood pressure and left ventricular hypertrophy in stroke-prone renovascular hypertensive rats with and without stroke, and observed the relationship between stroke and blood pressure and left ventricular hypertrophy after 10 weeks of antihypertensive treatment. Results Stroke rats had higher blood pressure and left ventricular hypertrophy than those without stroke. In the late antihypertensive period, the blood pressure level was not significantly different from that in the control group, but the stroke rate was significantly reduced with the reduction of left ventricular hypertrophy. Conclusions Both left ventricular hypertrophy and stroke are complications of hypertension, while the former is not an independent risk factor for the latter. Antihypertensive treatment to reduce left ventricular hypertrophy, even with mild hypoglycemia, is still relevant for the prevention of stroke