研究合成了壳聚糖水溶性衍生物Ａ，测定了Ａ的抑菌作用。结果证明Ａ物质确有较强的抑菌作用。对各种食品腐败菌的最小抑制浓度分别为：大肠杆菌０．５％，枯草杆菌０．５％，巨大芽孢杆菌１％，苏云金杆菌１％，青霉１％，毛霉０．５％，曲霉１％，根霉０．５％，啤酒酵母１％，该衍生物的抗菌作用对高温、高压稳定 The chitosan water-soluble derivative A was synthesized and the antibacterial activity of A was determined. The results show that A substance does have a strong antibacterial effect. The minimum inhibitory concentrations of various spoilage organisms were: Escherichia coli 0.5%, Bacillus subtilis 0.5%, Bacillus megaterium 1%, Bacillus thuringiensis 1%, Penicillium 1%, Mucor 0.5% Aspergillus 1%, Rhizopus 0.5%, Saccharomyces cerevisiae 1%, the derivatives of the antibacterial effect of high temperature and high pressure stability