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目的研究伴有2型糖尿病的良性前列腺增生症(BPH)患者行经尿道前列腺切除术(TURP)时,5%葡萄糖溶液作为TURP冲洗液的安全性。方法收集伴有2型糖尿病行TURP术的BPH患者21例,随机收集同期非糖尿病行TURP术的BPH患者52例作为对照。采集病历资料,统计年龄、国际前列腺症状评分(IPSS)、B超计算前列腺重量。术中采用5%GS作冲洗液行TURP术,统计分析两组患者术前、术中30 min、术后30 min和术后1 d即刻血糖,进一步分析两组在手术时间、冲洗液用量、切除腺体重量方面的差异。结果两组患者组内比较,血糖值均随手术时间延长逐渐升高,与术前相比有显著性差异(P<0.01),但术前、术中及术后血糖比较,组间无显著性差异(P>0.05)。无糖尿病相关的严重并发症发生。结论 TURP术中应用5%葡萄糖溶液作为冲洗液可引起血糖升高,但在充分术前准备和熟练手术操作情况下其作为冲洗液对于糖尿病患者也是相对安全的。
Objective To investigate the safety of 5% dextrose solution as a TURP irrigator during transurethral resection of the prostate (TURP) in patients with benign prostatic hyperplasia (BPH) accompanied by type 2 diabetes mellitus. Methods Twenty-one BPH patients with type 2 diabetes mellitus undergoing TURP and 52 BPH patients with non-diabetic TURP were enrolled as control. Collect medical records, statistical age, International Prostate Symptom Score (IPSS), B ultrasound calculated prostate weight. Intraoperative use of 5% GS as a flushing fluid TURP surgery, statistical analysis of two groups of patients preoperative and postoperative 30 min, postoperative 30 min and 1 d immediately after blood glucose, further analysis of the two groups in the operation time, the amount of irrigation fluid, The difference in resecting gland weight. Results In the two groups, the blood glucose level increased gradually with the prolongation of operation time, which was significantly different from that before operation (P <0.01). However, there was no significant difference between the two groups before and during surgery Sex differences (P> 0.05). No serious complications related to diabetes occur. Conclusion The application of 5% dextrose solution as a flushing solution in TURP can cause hyperglycemia, but it is also relatively safe for patients with diabetes mellitus to use as a flushing fluid under adequate preoperative preparation and skilled surgical procedures.