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目的探讨糖皮质激素依赖型类风湿性关节炎的临床治疗方法。方法75例患者在糖皮质激素逐渐减量同时,随机分为慢作用药MTX治疗组和消络痛治疗组,观察治疗6个月后比照治疗效果。结果MTX组总有效率高于消络痛组,但经统计学处理χ2=2.18<7.8l,故P>0.05,MTX组与消络痛组疗效差别无统计学意义。结论在糖皮质激素依赖型类风湿性关节炎病人逐步减少激素用量的同时,慢性用药MTX与消络痛的疗效差异无统计学意义。
Objective To investigate the clinical treatment of glucocorticoid-dependent rheumatoid arthritis. Methods 75 patients in the gradual reduction of glucocorticoid at the same time, were randomly divided into slow-acting MTX treatment group and the treatment group of analgesic effect observed after 6 months of treatment efficacy. Results The total effective rate of MTX group was higher than that of the group of analgesic painless. However, there was no significant difference between the two groups (P <0.05). Conclusions In the glucocorticoid-dependent rheumatoid arthritis patients gradually reduce the amount of hormones at the same time, the efficacy of chronic drug MTX and the elimination of painless There was no statistically significant difference.