论文部分内容阅读
目的研究缺血性心肌病(Ischemic Cardiomyopathy,ICM)型冠心病老年患者行丹参川芎嗪和环磷腺苷联合治疗对临床效果、心电图及预后的影响。方法选取本院2014年06月~2016年06月收治的ICM型冠心病104例老年患者资料进行分析,按照临床选择的不同治疗方案分成2组,均为52例,将行常规+安慰剂治疗患者作为对照组,将行丹参川芎嗪和环磷腺苷联合治疗患者作为观察组,对两组临床效果、心电图及预后情况加以对比分析。结果观察组治疗后6min步行距离(282.55±30.30)m比对照组(243.53±30.20)m长,且步行后心肌耗氧量、心率值改善效果均比对照组优(p<0.01);观察组心电图总有效率71.15%比对照组51.92%高,且预后心功能指标水平均比对照组优(p<0.05,p<0.01)。结论 ICM型冠心病老年患者行丹参川芎嗪和环磷腺苷联合治疗效果满意,能够延长患者6min步行距离,改善心肌耗氧量、心率值和心电图效果,且促进患者心功能改善,值得临床推广及应用。
Objective To investigate the clinical effects, electrocardiogram (ECG) and prognosis of combined treatment of ligustrazine and cyclophosphamide on elderly patients with coronary heart disease with ischemic cardiomyopathy (ICM). Methods The data of 104 elderly patients with ICM coronary heart disease admitted from June 2014 to June 2016 in our hospital were analyzed and divided into two groups according to the different treatment options of clinical choice. All of them were 52 and were treated with routine + placebo Patients as control group, the line Salvia Ligustrazine and cyclic adenosine monophosphate combined treatment of patients as the observation group, the clinical effect of the two groups, electrocardiogram and prognosis were compared. Results The walking distance (282.55 ± 30.30) m in the observation group after treatment was (243.53 ± 30.20) m longer than that in the control group (P <0.01), and the myocardial oxygen consumption and heart rate after walking were better than those in the control group The total effective rate of electrocardiogram was 71.15% higher than 51.92% of the control group, and the prognosis of cardiac function index was better than the control group (p <0.05, p <0.01). Conclusion ICM coronary heart disease in elderly patients with Salvia ligation of tetramethylpyrazine and corticosteroids with satisfactory results, can extend the patient 6min walking distance, improve myocardial oxygen consumption, heart rate and ECG results, and improve cardiac function in patients with deserved clinical promotion And application.