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目的调查Ⅰ类切口手术患者围术期预防性应用抗菌药物的情况,以期为临床的合理应用提供依据。方法随机抽取2012年1月至12月Ⅰ类切口手术住院患者病历166份,分析其抗菌药物的应用情况。结果抗菌药物使用率85.5%,病原学送检率7.7%,使用强度55.77。选用品种主要为阿莫西林/舒巴坦、头孢西丁与头孢曲松。在48 h内预防用药占20.4%,术前0.5~2 h给药的占7.0%。结论Ⅰ类切口预防性应用抗菌药物存在不合理现象,需加强抗菌药物使用的培训及管理,促进临床抗菌药物的正确选择和使用。
Objective To investigate the perioperative prophylactic use of antibacterials in patients undergoing type Ⅰ incision surgery in order to provide a basis for the rational clinical application. Methods A total of 166 medical records of patients with type Ⅰ incision in January 2012 to December were randomly selected and analyzed for their antimicrobial application. Results The antibacterial drug use rate was 85.5%, the etiological rate was 7.7%, and the intensity of use was 55.77. Selected varieties are mainly amoxicillin / sulbactam, cefoxitin and ceftriaxone. Preventative medication accounted for 20.4% within 48 h and pretreatment 0.5 to 2 h accounted for 7.0%. Conclusions Class I incision is an unreasonable use of prophylactic antimicrobial agents. Training and management of antimicrobial agents need to be strengthened to promote the correct choice and use of clinical antimicrobial agents.