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目的:研究白饭树不同提取物(氯仿提取物及水提物)对小鼠佐剂性关节炎(AA)的治疗作用。方法:观察白饭树氯仿提取物及水提物对AA小鼠给药后继发性足肿胀、胸腺系数(胸腺/体质量)、脾系数(脾/体质量)的变化。结果:氯仿提取物组、水提物组,地塞米松组对小鼠继发性足肿胀有明显的抑制作用,减轻胸腺和脾脏质量。结论:白饭树中脂溶性物质和水溶性物质均可减轻AA小鼠继发性足肿胀。
Objective: To study the curative effect of different extracts (extract of chloroform and water extract) on the adjuvant arthritis (AA) in mice. Methods: The changes of secondary paw edema, thymus coefficient (thymus / body weight), spleen coefficient (spleen / body weight) after administration of chloroform extract and water extract of white rice tree to AA mice were observed. Results: The chloroform extract group, water extract group and dexamethasone group significantly inhibited the secondary foot swelling of mice and reduced the quality of thymus and spleen. CONCLUSION: Lipid-soluble and water-soluble substances in Radix Et Rhizoma can alleviate secondary foot swelling in AA mice.