西米替丁静注时,约60～70%以原型从肾排泄,肾功能低下的患者应注意其用量。作者用肥胖者和正常体重的人各6名(均是男性2名、女性4名)进行对比试验,研究两组问西米替丁体内动力学的差别。平均体重±标准偏差,正常组是62±7kg,肥胖 Cimetidine intravenous injection, about 60 to 70% of the prototype excreted from the kidneys, renal dysfunction in patients should pay attention to their dosage. The authors used obese and normal-weight people each 6 (two were males, four females) comparative study to study the difference between the two groups of cimetidine kinetics. Mean body weight ± standard deviation, normal group is 62 ± 7kg, obesity