为了制作适合于法医学应用的 DNA 芯片,选择了法医学常用的基因位点-HLA-DQα位点,设计了特异性地扩增该位点特定部位的 PCR 引物,以及该位点各等位基因亚型的特异性探针,制作了检查该基因位点等位基因型的芯片,结果显示了所设计的 PCR 引物和各等位基因型探针的特异性,以及实际应用的可能性。 In order to make a DNA chip suitable for forensic applications, we selected the HLA-DQα locus, a common locus for forensic science, and designed PCR primers that specifically amplify specific sites of this locus. Type specific probe, a chip for examining the allele of the gene locus was made and the result shows the specificity of the designed PCR primer and each allele probe, and the possibility of being practically used.