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放射性脑坏死是鼻咽癌放射治疗的严重併发症之一。本文就1977年7月至1987年底收入湖南省肿瘤医院放疗科行首程根治性放射治疗病例中,併发放射性脑坏死7例的资料进行分析和讨论。 一般资料 男6例,女1例。年龄26～63岁。鼻咽部低分化鳞癌6例,低分化腺癌1例。除1例只放疗一程外,6例于发生脑坏死之前鼻咽部接受过再程放疗,最多1例在三年间放疗三程,首程与再次放疗间隔6～58个月,平均18.7月,间隔不足一年者2例。鼻咽部用~(60)钴外照射,首程剂量为常规分次,67—75.8G Y。NSD1855～2028ret,其中耳前野剂量53～62G Y。
Radiation brain necrosis is one of the serious complications of radiotherapy for nasopharyngeal carcinoma. This article analyzes and discusses the data of 7 cases of radioactive brain necrosis in the first course of radical radiotherapy from Radiotherapy Department of Hunan Provincial Cancer Hospital from July 1977 to the end of 1987. General information Male 6 cases, female 1 case. Age 26 to 63 years old. Nasopharyngeal poorly differentiated squamous cell carcinoma in 6 cases, poorly differentiated adenocarcinoma in 1 case. Except for 1 case of radiotherapy alone, 6 patients received retransmission radiotherapy in the nasopharynx before cerebral necrosis occurred. Up to 1 patient received radiotherapy for 3 cycles in 3 years. The interval between first and second radiotherapy was 6 to 58 months, with an average of 18.7 months. There are 2 cases with intervals less than one year. The nasopharynx was externally irradiated with ~(60) cobalt, and the first dose was conventionally graded, 67-75.8G Y. NSD1855～2028ret, in which the wild dose in front of the ear is 53～62G Y.