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目的观察激素吸入联合孟鲁司特治疗小儿中重度支气管哮喘的临床效果。方法将小儿中重度支气管哮喘患儿85例根据治疗方法分为观察组45例和对照组40例,观察组给予激素吸入联合孟鲁司特治疗,对照组给予激素吸入治疗,治疗后比较2组患儿喘息症状发作次数及咳嗽症状缓解和消失时间。结果治疗前2组喘息症状发作次数比较差异无统计学意义(P>0.05),治疗后2组喘息症状发作次数均降低(P<0.05),且观察组低于对照组(P<0.05)。观察组咳嗽症状缓解时间及消失时间均短于对照组,差异均有统计学意义(P<0.05)。结论激素吸入联合孟鲁司特治疗小儿中重度支气管哮喘患儿疗效显著,可有效改善患儿症状,最终提高患儿的生活质量。
Objective To observe the clinical effect of hormone inhalation combined with montelukast on children with moderate and severe bronchial asthma. Methods 85 cases of children with moderate and severe bronchial asthma were divided into observation group 45 cases and control group 40 cases, the observation group were given hormone inhalation combined with montelukast, while the control group were treated with hormone inhalation. After treatment, two groups were compared Childhood wheezing symptoms episodes and cough symptoms alleviate and disappear time. Results There was no significant difference in the number of wheezing episodes between the two groups before treatment (P> 0.05). The number of wheezing episodes in both groups decreased after treatment (P <0.05), and the observation group was lower than the control group (P <0.05). Cough symptom relief time and disappearance time in the observation group were shorter than the control group, the difference was statistically significant (P <0.05). Conclusion Hormone inhalation combined with montelukast treatment of pediatric patients with moderate and severe bronchial asthma significant effect, can effectively improve children’s symptoms, and ultimately improve children’s quality of life.