中枢神经系统缺氧缺血后 ,选择性易损性是神经生理的一个重要方面 ,此不仅导致细胞的损伤 ,还可阻止脑组织的正常能量供应。90年代以来 ,随着生理、生化、电生理技术的不断发展 ,通过各种缺氧缺血模型 ,对内源性腺苷及其衍生物对中枢神经元活动的影响进行了一系列研究 ,从而证 Selective vulnerability after central nervous system hypoxia-ischemia is an important aspect of neurophysiology that not only causes cell damage but also prevents normal energy supply to brain tissue. Since the 1990s, with the continuous development of physiology, biochemistry and electrophysiology, a series of researches on the effects of endogenous adenosine and its derivatives on the activities of central neurons have been carried out through various hypoxic-ischemic models.