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最近急性白血病的治疗成绩很大,特别是小儿急性淋巴细胞性白血病的生存期显著延长(中数生存期33个月),但成人急性白血病的疗效仍差。从不同年龄的死亡率来看,近年来高龄者的死亡率在增加。目前对成人急性白血病的治疗迫切需要寻找有效的治疗方案。根据报导,成人急性粒细胞性白血病平均生存期多不超过一年,最近也看到过超过一年的报告。从不同年龄的缓解率看,根据山田氏报告,小于40岁的有75%,40岁以上的9例中,只有2例完全缓解,由此可知高龄者不易达到完全缓解,最近看到超过5年的生存病例。而不满14岁的儿童却超过80%。
Recently, the treatment of acute leukemia has been very successful, especially the survival of children with acute lymphoblastic leukemia is significantly prolonged (median survival of 33 months), but the efficacy of acute leukemia in adults is still poor. In terms of mortality rates at different ages, the mortality rate of elderly people has increased in recent years. At present, the treatment of adult acute leukemia urgently needs to find an effective treatment plan. According to reports, the average survival of adult acute myelogenous leukemia is less than one year, and more than one year has been reported recently. Judging from the response rates of different ages, according to the Yamada report, 75% of those under the age of 40 and 9 of those over the age of 40 had complete remission. This shows that it is not easy for the elderly to achieve complete remission, and recently seen over 5 Years of survival. Children under 14 are over 80%.