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目的研究肾综合征出血热(HFRS)相关流行因素。方法将1991-2006年江苏省赣榆县HFRS发病资料分别按年龄、性别、职业、地理、季节、年降水总量、年粮食产量、人均GDP、动物宿主因素和疫苗接种因素进行归类分析。结果1991年以来,赣榆县HFRS疫情下降明显,男性、农民、20～59岁人群占有较高的发病比重。一年中存在春季和秋季发病高峰,尤以秋冬峰为高;地理分布存在典型的丘陵山区>内陆平原>沿海的特点;年粮食产量与疫情波动正相关。结论人均GDP与疫情波动呈负相关;对适龄人群开展大规模疫苗接种对控制HFRS疫情起着决定性作用。
Objective To study the epidemiological factors related to hemorrhagic fever with renal syndrome (HFRS). Methods The incidence of HFRS in Ganyu County of Jiangsu Province from 1991 to 2006 were classified by age, sex, occupation, geography, season, total annual precipitation, annual grain yield, per capita GDP, animal host and vaccination factors. Results Since 1991, the epidemic situation of HFRS in Ganyu County has dropped significantly. Male, peasants and 20- to 59-year-olds have a relatively high incidence. There was a peak in spring and autumn in one year, especially in autumn and winter. The geographical distribution was typical of hilly area> inland plain> coastal area. The annual grain yield was positively correlated with the fluctuation of epidemic situation. Conclusions The per capita GDP is negatively correlated with the outbreak of epidemic situation. Large-scale vaccination of the right age group plays a decisive role in controlling the epidemic of HFRS.