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目的探讨支气管哮喘患者支气管舒张试验指标与临床疗效的关系。方法选取2013年6月—2014年10月深圳市龙华新区人民医院收治的88例支气管哮喘患者。根据支气管舒张试验结果,将其分为对照组(阴性)和试验组(阳性)各44例。所有患者采用西医对症治疗,记录并分析两组患者治疗前后的支气管舒张试验指标和临床疗效。结果治疗前试验组患者第一秒用力呼气容积(FEV1)增加绝对值、FEV1增加率、呼吸峰流速(PEF)增加绝对值高于对照组(P<0.05);治疗后试验组患者FEV1增加绝对值、FEV1增加率、PEF增加绝对值均低于对照组(P<0.05)。治疗后两组患者FEV1增加绝对值、FEV1增加率、PEF增加绝对值均低于治疗前(P<0.05)。试验组患者临床疗效优于对照组(P<0.05)。结论常规解痉治疗可以改善支气管哮喘患者的支气管舒张试验指标,且支气管舒张阳性患者的临床疗效优于阴性患者。
Objective To investigate the relationship between bronchodilator test and clinical curative effect in patients with bronchial asthma. Methods 88 patients with bronchial asthma admitted from June 2013 to October 2014 in Longhua New District People’s Hospital of Shenzhen City were selected. According to bronchodilator test results, divided into control group (negative) and test group (positive) in 44 cases. All patients with Western symptomatic treatment, records and analysis of two groups before and after treatment of bronchodilator test indicators and clinical efficacy. Results Before treatment, FEV1 increased absolute value, FEV1 increased and PEF increased absolute value higher than that of control group (P <0.05), FEV1 of experimental group increased after treatment The absolute value, the increase rate of FEV1 and the absolute value of PEF increase were lower than those of the control group (P <0.05). After treatment, FEV1 increased absolute value, FEV1 increased rate, PEF increased absolute value was lower than before treatment (P <0.05). The clinical efficacy of the experimental group was better than that of the control group (P <0.05). Conclusion Conventional antispasmodic therapy can improve bronchodilator test in patients with bronchial asthma, and the clinical efficacy of bronchodilation positive patients is better than negative patients.